I guess you can use most of the key color correction tools in 48 bit mode in Photoshop, like Levels, Curves, Hue/Sat etc. But you can't use most of the filters, nor layers, nor adjustment layers.
You can do that if you wish. It probably won't save you much scan time (on my scanners it takes the same amount of time to scan in either mode) To some extent but will save you disk space.
Yes, the scanner internally scans in high bit mode and then converts to 24 bit mode. That's why it doesn't save you any time to just scan in 24 bits
You can do many things in 48 bit mode, but not copy/paste.
The normal flow for people truly using 48 bit mode is to make the major overall tonal corrections in high bit mode and then convert to 24 bit mode for local corrections.
Here' are two explanations of why high bit mode is better in theory, if you make a lot of changes to the colors, etc. At least the histograms look better (grin).
http://www.creativepro.com/story/fewature/7627.html
http://www.inkjetart.com/2450/48bit/page4.html
In theory this makes a lot of sense, in practice it's often hard to see any differences in the final output and some people feel it's not worth the extra disk space and effort, Dan Margulis exceedingly being the most well-known proponent of this view.